Medical Applications of Molecular Biology
BSc-597

Syllabus (Fall 2009)                                                                 Return to home page

Research Paper Guidelines

Guide to Reading Scientific Papers
Caveat to Reading Scientific Papers
                                                                                    
Example Exam with answer key

Midterm Exam Answer Key
10 Quiz Summary

Paper Downloads

notes on common methods

Drug Design and Delivery Systems
combinatorial chemistry for drug design- Jones and Diamond, ACS Chemical Biology (2007) 2: 718-24.
microencapsulated cell delivery- Wen et al., Journal of Gene Medicine (2006) 8: 362-9.
discovering phosphatase inhibitors- Tautz and Mustelin, Methods (2007) 42: 250-260.
coacervate gel delivery of protein drugs- Jin et al., Journal of Controlled Release (2008) 127: 249-256.
drug carrying phage nanoparticles- Bar et al., BMC Biotechnology (2008) 8:37-51.
anti-influenza rational drug design-  Bantia et al, Anti-microbial Agents and Chemotherapy (2001) 45: 1162-7.

Viruses
review paper- Kliger et al., Drug Discovery Today (2005) 10:345-52.
RNAi as an anti-influenza therapy-  Ge et al, Proceedings of the National Academy of Sciences, USA (2003) 100:2718-23.
viral delivery of an anitviral shRNA- Chen et al, Gene Therapy (2007) 14:11-19.
hpv vaccine reducing cervical cancer- Ohlschlager et al, Vaccine (2006) 24: 2880-93.

Cancer
hpv anti-cancer phase II clinical trial- Villa et al, Oncology (2005) 6: 271-8.
cancer metastasis review- Sierra, Drug Resistance Updates (2005) 8: 247-57.
capturing circulating cancer cells- Nagrath et al., Nature (2007) 450: 1235-39.
identifying prostate cancer types- True et al., Proceedings of the National Academy of Sciences, USA (2006) 103: 10991-96.
blocking telomerase function- Djojosubroto et al., Hepatology (2005) 42: 1127-36.
inhibitors of angiogenesis- Huang et al., Oncogene (2001) 20: 4188-97.
development of chemotherapy resistance- Griswald et al, Molecular and Cellular Biology (2006) 26: 6083-92.
DNA sequencing powerpoint and next-generation sequencing pdf
differences between metastatic and primary breast tumors- Shah et al, Nature (2009) 461: 809-13.

Diabetes
differentiating bone marrow into pancreas- Tang et al., Diabetes (2004) 53:1721–32.
pancreatic endoderm from embryonic stem cells- Kroon et al., Nature Biotechnology (2008) 26: 443-52.

Stem Cell Biology
Parkinson's treatment with neural stem cells- Redmond et al., Proceedings of the National Academy of Sciences, USA (2007) 104: 12175-80.
mobilizing hematopoetic stem cells to cure Alzheimers- Tsai et al., Journal of Experimental Medicine (2007) 204: 1273-80.
stem cells for hemophilia- Moayeri et al., Molecular Therapy (2005) 12: 1034-42.
cardiac stem cells- Hahn et al., Journal of the Americal College of Cardiology (2008) 51: 933-43.
induced pluripotent stem cells-Wernig et al,  Proceedings of the National Academy of Sciences, USA (2008) 105: 5856-61.