Syllabus (Spring 2008)                                                                 Return to home page

Research Paper Guidelines

Guide to Reading Scientific Papers
Caveat to Reading Scientific Papers
                                                                                    
Example Exam with answer key

Exam #1  Thursday April 3
paper outline Tues  April 8

Presentations:  April 22 and 24
Final Papers Due April 29th

Final Exam Thursday May 8th, 2008  at 8:00 AM! (yuck)

Paper Downloads

notes on common methods

Viruses
review paper- Kliger et al., Drug Discovery Today (2005) 10:345-52.
RNAi as an anti-influenza therapy-  Ge et al, Proceedings of the National Academy of Sciences, USA (2003) 100:2718-23.
anti-influenza rational drug design-  Bantia et al, Anti-microbial Agents and Chemotherapy (2001) 45;1162-7.
viral delivery of an anitviral shRNA- Chen et al, Gene Therapy (2007) 14:11-19.
hpv vaccine reducing cervical cancer- Ohlschlager et al, Vaccine (2006) 24: 2880-93.

Cancer
hpv anti-cancer phase II clinical trial- Villa et al, Oncology (2005) 6: 271-8.
cancer metastasis review- Sierra, Drug Resistance Updates (2005) 8: 247-57.
capturing circulating cancer cells- Nagrath et al., Nature (2007) 450: 1235-39.
identifying prostate cancer types- True et al., Proceedings of the National Academy of Sciences, USA (2006) 103: 10991-96.
blocking telomerase function- Djojosubroto et al., Hepatology (2005) 42: 1127-36.
inhibitors of angiogenesis- Huang et al., Oncogene (2001) 20: 4188-97.
discovering phosphatase inhibitors- Tautz and Mustelin, Methods (2007) 42: 250-260.

Michael Hanna- single cell gene expression in retina- Hanna and Coskun, Molecular Vision (2007) 13: 2194-208.
development of chemotherapy resistance- Griswald et al, Molecular and Cellular Biology (2006) 26: 6083-92.

Diabetes
transplantation monitoring/ gene transfection over time- Lu et al., Molecular Therapy (2004) 9:428-35.
differentiating bone marrow into pancreas- Tang et al., Diabetes (2004) 53:1721–32.
pancreatic endoderm from embryonic stem cells- Kroon et al., Nature Biotechnology (2008) epub.

Stem Cell Biology
Parkinson's treatment with neural stem cells- Redmond et al., Proceedings of the National Academy of Sciences, USA (2007) 104: 12175-80.
mobilizing hematopoetic stem cells to cure Alzheimers- Tsai et al., Journal of Experimental Medicine (2007) 204: 1273-80.
stem cells for hemophilia- Moayeri et al., Molecular Therapy (2005) 12: 1034-42.
cardiac stem cells- Hahn et al., Journal of the Americal College of Cardiology (2008) 51: 933-43.

Drug Delivery Systems
microencapsulated cell delivery- Wen et al., Journal of Gene Medicine (2006) 8: 362-9.
coacervate gel delivery of protein drugs- Jin et al., Journal of Controlled Release (2008) 127:249-256.
drug carrying phage nanoparticles- Bar et al., BMC Biotechnology (2008) 8:37-51.